This article conducts a desk review on the impact of artificial intelligence on employment trends in various countries worldwide, with a focus on the United States as a representative example, and the demands it places on universities in Vietnam. The research highlights that artificial intelligence (AI) is reshaping future career trends and the required skill sets for the workforce. Higher education, as the hub for cultivating skilled and highly qualified human resources, must create optimal conditions for training a workforce that can meet the demands of digital transformation and the significant influence of AI. In the context of a developing countries like Vietnam, universities also need to innovate their curriculum and foster closer partnerships between academia and industry to equip students with lifelong learning skills.