In this study, we investigated adsorptive removal of copper ion Cu2+ in water environment using nanosilica fabricated from rice husk. The nanosilica was characterized by X-ray diffraction (XRD), and energydispersive X-ray spectroscopy (EDX). Some parameters for removal of Cu2+ using nanosilica through adsorption technique were adsorption time 90 min, pH 7 and adsorbent dosage 10 mg/mL. Under optimum conditions, maximum removal of Cu2+ reached to 98.7 %. Adsortion capacity of Cu2+on nanosilica decreased with increasing ionic strength while adsorption capacity reached to 50.0 mg/g. Adsorption of Cu2+ on nanosilica in the presence of antibiotic ciprofloxacin (CFX) was higher than that in the absence of CFX. Adsorption isotherms were well fitted by Freundlich model, suggesting that adsorption induced by both electrostatic and non-electrostatic interactions.