"An Intuitive, Interactive Introduction to Biostatistics" is an introductory statistics textbook oriented towards towards undergraduate students in the health sciences. While covering the breadth of material typically presented in a first semester statistics course, including introductions to probability and distributions, study design, CLT, hypothesis testing, and inference, IIIB distinguishes itself with its focus on cultivating student intuition through the use of guided questions and interactive simulation-based applets. Written in R, this open-source text has been created with customizability in mind, offering instructors maximal flexibility in arranging and modifying the content.