The present book contains ten articles illustrating the different possible uses of UAVs and satellite remotely sensed data integration in Geographical Information Systems to model and predict changes in both the natural and the human environment. It illustrates the powerful instruments given by modern geo-statistical methods, modeling, and visualization techniques. These methods are applied to Arctic, tropical and mid-latitude environments, agriculture, forest, wetlands, and aquatic environments, as well as further engineering-related problems. The present Special Issue gives a balanced view of the present state of the field of geoinformatics.