Viruses and Nuclear Egress

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Tác giả: Donald M Coen

Ngôn ngữ: eng

ISBN-13: 978-3036556956

ISBN-13: 978-3036556963

ISBN: books978-3-0365-5695-6

Ký hiệu phân loại:

Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022

Mô tả vật lý: 1 electronic resource (182 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 372901

 This Special Issue of Viruses focuses on the topic of viruses and nuclear egress. Nuclear egress is a fascinating process by which herpesvirus nucleocapsids make their way from the nuclear interior to the cytoplasm. As nuclear egress and the viral proteins that orchestrate it differ from host processes and proteins in important ways, there is interest in targeting antiviral therapies to disrupt this process. Indeed, the recently approved drug maribavir acts in large part by inhibiting a step of nuclear egress. The Special Issue includes five reviews-three on nuclear egress of two alphaherpesviruses, herpes simplex virus and pseudorabies virus
  one on a betaherpevirus, human cytomegalovirus
  and one on a gammaherpesvirus, Epstein-Barr virus-and five research papers-two on alphaherpesviruses and three on human cytomegalovirus.
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