Kidney transplantation brings new life for millions of ESRD patients on the world. Currently, many countries have performed kidney transplantations with Rh incompatibility. At Hue Central Hospital, we have also successfully transplanted kidneys in 2 cases with donor and recipient had different Rhesus factors. In 2013 and 2019, Hue Central Hospital, we have performed kidney transplants with two Rh incompatibility cases. First case with recipient Rh(-) and donor Rh(+). Another case, recipient Rh(+) and donor Rh(-).In clinical, both patients have healthy life and normal kidney function with serum uremia 6,4 mmol/l, serum creatinine: 109 (µmol/l)
serum uremia 7,4 mmol/l, serum creatinine: 108 (µmol/l). The Rh incompatibility factor does not affect kidney transplantation outcome and post-transplant treatment.