The patient, a 22-year-old female, was diagnosed with diffuse large B-cell lymphoma (an aggressive non-Hodgkin’s lymphoma). The patient had completed 6 cycles of R-CHOP (from March 2018 to July 2018). After that, the patient was re-examined regularly monthly (manifested with moderate and hypochromic anemia, bone marrow aspiration was negative for malignancy). In November 2019, the complete blood cell (CBC) findings were as follows: White blood cell (WBC) count 81 x109 /liter, neutrophils 7%, lymphocytes 22%, monocytes 2%, blasts 69%
red blood cell count 2.6 x 106 /ml, hemoglobin 7.8 g/dl, platelet count 192.000. Bone marrow (BM) aspiration: acute myeloid leukemia (AML5?) (81% blasts in BM)
blast cells were positive for PAS, myeloperoxidase (MPO) and sudan black negative. The bone marrow biopsy: myeloid malignant proliferation. Cluster of Differentiation (CD): positive for CD13, CD33, CD64, HLA-DR, CD (±): CD117, CD14, CD 16, CD34
negative for: CD11b, CD35, CD71, CD15, CD19, CD20, CD7, CD3, CD38
monoblasts composed 90% of bone marrow cells.