Challenges and Opportunities for Effective Cancer Immunotherapies

• Tác giả: Michael Kershaw, Clare Slaney
• Ngôn ngữ: eng
• ISBN-13: 978-3036569604
• ISBN-13: 978-3036569611
• ISBN: books978-3-0365-6961-1
• Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Mô tả vật lý: 1 electronic resource (500 p.)
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 376258
• Chủ đề: 1. CD44; 2. interleukin-15; 3. monoclonal antibodies; 4. near infrared photoimmunotherapy; 5. Medicine

Tóm tắt

Anti-cancer immunotherapies have generated spectacular outcomes in the clinical environment and changed treatment schemes for cancer patients. Adoptive cell therapies (ACTs), including using autologous tumor-infiltrating lymphocytes and chimeric antigen receptor (CAR) T cells, and checkpoint blockades have emerged as the most effective treatments for certain cancers. The current challenge for cancer immunotherapies is that although some patients have benefited from the treatments, a number of cancers are resistant. The purpose of this Special Issue is to understand anti-cancer immunotherapy treatment resistance mechanisms and explore new options to provide opportunities for effective treatments.