Pathogenesis and Targeted Therapy of Epilepsy

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Tác giả: Prosper N'Gouemo

Ngôn ngữ: eng

ISBN-13: 978-3036564364

ISBN-13: 978-3036564371

ISBN: books978-3-0365-6437-1

Ký hiệu phân loại:

Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023

Mô tả vật lý: 1 electronic resource (236 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 376541

Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called "pharmaco-resistant epilepsy" or "refractory epilepsy." Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint's original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
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