Introduction Ischemia Modified Albumin: Coronary artery lesions were the main cause of acute cerenary sym dereme (ACS), the character of coronary artery lesion and how is IMA concentrations correlated with degree of coronary artery lesion in acute coronary syndrome? Objective: Survey character of coronary artery lesions in patients with acute coronary syndrome through the results of angiography and correlation between the concentration of IMA and degree of coronary artery lesions in patients with acute coronary syndrome. Subject and Method: 130 patients at the Cardiology Center-Hue Central Hospital are diagnosed acute coronary syndrome according to the Fourth universal definition of myocardial infarction 2018. In which 103 patients were taken angiography and evaluated the coronary artery lesions follow GENSINI scale. Result: Research conducted on 130 patients, including 85 males and 45 females with the proportion of male: female was 1.89, average age: 65.7 ± 12.3years old. There were 91.3% of patients with coronary artery lesions higher than coronary artery non lesions (p <
0.001). Injury of one branch accounted for 35,9%, two branch accounted for 34.0% and three branch injuries accounted for 21.4%. There were 79.6% in LAD injury and 58.3% in RCA, accounting for 41.7% in LCx. The lesions stenosis that more than 75% was accounted for the highest percentage 70.59%. GENSINI score average was 27.80 ± 25.92 and median score was 21 points. There was no correlation between the concentration of IMA and the branching coronary lesions with r = - 0,046, p >
0.05. There was no correlation between the concentration of IMA and GENSINI scores with r = - 0,064, p>
0,05. Conclusions: The percentage of LAD lesions was highest the percentage of lesions more than one coronary artery branch was high and severe coronary stenosis is highest proportion in acute coronary syndrome. There was no correlation between the IMA concentration and the number of branching coronary lesions, as well as GENSINI scores.