Light-Controlled Modulation and Analysis of Neuronal Functions

• Tác giả: Piotr Bregestovski, Carlo Matera
• Ngôn ngữ: eng
• ISBN-13: 978-3036565620
• ISBN-13: 978-3036565637
• ISBN: books978-3-0365-6562-0
• Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Mô tả vật lý: 1 electronic resource (200 p.)
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 377547
• Chủ đề: 1. c-fos; 2. fear memory; 3. parietal association cortex; 4. Biology, life sciences; 5. Research & information: general

Tóm tắt

 Contemporary research has been enriched by new directions in which light plays a key role as a tool for the modulation of cellular activity and the invasive monitoring of intracellular ions and other components. The progress in molecular biology, imaging techniques and other modern technologies has led to the emergence of three main areas in which light is the main tool: optogenetics, photopharmacology, and optosensorics. The main advantages of these approaches are the possibilities to investigate the functions of cells
  modulate the activity of ion channels, synaptic transmission and neuronal circuits
  measure concentrations of ions and other cellular components
  and even control the behaviour of organisms.Due to the development of these powerful molecular and genetic tools, our understanding of the mechanisms underlying the functioning of the nervous system has greatly advanced. This reprint is intended to highlight the latest advances in these areas with a primary focus on light-based analysis and control of neuronal functions.