Objective: To examine self-management and determine associations between child gender, severity of illness, social support and self-management of Vietnamese school-age children with asthma.Method: A descriptive predictive cross-sectional study was used. Sample included 91 Vietnamese school-age children who came to the Outpatient department of the Hue central hospital, to follow up treatment for asthma. Data were collected from March 2017 to October 2017. Research instruments included a demographic questionnaire, the asthma self-management inventory for children, the severity of illness scale for asthma, and the social support questionnaire for children. Internal consistency reliabilities were 0.84, 0.83 and 0,89 respectively. Data were analysis by using the spss 17 programResults: Results showed that mean total score of self-management was 46.37 (S.D. = 5.66), which was at a moderate approaching to high level. Child gender (boys) was the best predictor accounted for 28.3% in the prediction of self-management (B= -5.765, p<
0.001), followed by severity of illness (B=-0.456, p<
0.001) and social support B= 0.059, p<
0.05) accounted for 16.2% and 4.3%, respectively. The three significant predictors accounted for 48.8 % of variance in asthma self-management of Vietnamese schoolage children (F 3, 87 = 22.121, p<
0.001).Conclusions: These findings suggest that nurses and health care providers in relation to children with asthma could increase self-management of children with asthma through promote and strengthen social support, especially for boys and illness severity.