Background: The aim of this study is to research the modified Blumgart pancreaticoduodenectomyanastomosis procedure and complications following surgery and corresponding treatment strategies.Methods: From January 2010 to January 2020, 87 patients with pancreatic disease were performed themodified Blumgart pancreaticoduodenectomy procedure after pancreaticoduodenectomy at Hue Central Hospital.Results: The mean age was 59.5 ± 11 (18 - 83) years, the male/female ratio was 2.1. Predominant symptoms included abdoninal pain (66.7%), jaundice (78.7%), weight loss (56.6%) and pruritus (58.5%).Hardened pancreatic texture was found in 11,3% whereas soft, non-fibrotic pancreatic texture accountedfor the majority of cases (88.7%). We performed prophylactic external pancreatic duct drainage in 76% ofcases. Mean blood transfusion volume was 571.9 ± 251.0 (350 - 1350) ml. Mean operative time was 280 ±28.9 minutes. There were 32% of patients having post-operative complications, including pancreatic fistula(2,4%), haemorrhage (5.7%), transient acute pancreatitis (13.2%), delayed gastric emptying (7.5%) andbilioenteric anastomosis fistula (1.2%) and post-operative mortality was 1.2%.Conlusions: Overall complications rate after pancreaticoduodenectomy with pancreaticojejunostomywas still high but the rates of pancreatic fistula and haemorrhage were low.