Background: Infection with Covid 19 and sepsis is a severedisease that leads to a high risk of death. This study aims to describe the characteristics of Covid-19 patients with positive blood culture, elements of bacteria causing sepsis, and the level of antibiotic response of bacteria on the antibiotic chart. Methods: A cross - sectional descriptive study was conducted on 26 Covid-19 patients with positive blood culture 8/2021-10/2021. Result: Twenty - six Covid-19 patients had an average age of 57.89 years (range: 32 - 78). Of these, 57.7% of patients were older than 60 years
women were more than men. 69.23% of patients had a medical history of the disease. The average treatment time was 16.35 days
84.62% of patients had positive blood cultures after 48 hours of treatment. 23.08% of patients were recovered after treatment. 96.15% of patients increased CRP, 100% of patientsincreased Procalcitonin, and 86.46% increased leukocytosis and neutrophils. The bacteria that caused the most sepsis are Acinetobacter baumannii, Escherichia coli, Burkholderia cepacia with 19.23%. Gram - negative bacteria were most sensitive to Carbapenem, Aminoglycoside antibiotics. Gram - positive bacteria were more susceptible to Linezolid and Vancomycin antibiotics. Conclusion: Sepsis with positive blood culture in covid patients increases the mortality rate. Identifying bacterial strains and appropriate aggressive antibiotic treatment for each bacterial is necessary.