Purpose: In this study, we evaluated the effectiveness of radiofrequency ablation with systemic chemotherapy in the treatment of colorectal cancer with liver metastasis at K hospital. Methods: 30 patients with colorectal cancer liver metastasisin K hospital were retrospectively evaluated the effectiveness of radiofrequency ablation with systemic chemotherapy from January 2017 to August 2020. Results: The responserate after 4 cycles and 8 cycles of chemotherapy was 73.3% and 85.2%, respectively. 100% of the patients had a tumor response after radiofrequency ablation. A complete response was 63.3%, and a partial response was 36.7% according to the International Intervention Photovoltaic Society standards. The progression - free survival was 16.7 ± 1.42 months. After radiofrequency ablation: all patients with mild to moderate hepatic pain, 10% of patients have fever, increased liver enzymes encountered in 90% of patients. Conclusion: Radiofrequency ablation combination with systemic chemotherapy was safe
it showed efficacy in patients with liver metastasis after surgery for colorectal cancer and can be a preferred treatment.