Background: Medical incidents are undesirable situations that occur in diagnosis, healthcare and treatment due to objective and subjective factors, which aren’t due to the disease process or the patient’s location affecting the health and life of the patient. This problem is one of the most worrying issues in providing safe healthcare services for patients/customers. This study aims to describe the characteristics of medical incidents occurring at Hue Central Hospital in 2021. Methods: A cross - sectional descriptive study was conducted on 447 medical incidents which were reported to the Quality Management Department of Hue Central Hospital during the period from January 1, 2021 to December 31, 2021. Results: Incidents were detected the most in - patient rooms (87.5%) and were reported the most by the staff of clinical departments (92.6%). The time when medical incidents occurred the most was in the afternoon with 47.9%. There were 90.4% of medical incidents that had a direct impact on the patient. Moderate and severe lesions accounted for a high and relatively similar rate (38.9% and 36.9%). Incidents of hospitalacquired infections showed the highest rate with 70.0%. Conclusions: Hospital - acquired infections are the main group of medical incidents occurring at Hue Central Hospital. There were no serious medical incidents occurring during the study period.