According to regulations of the Ministry of Education and Training, vocational education is currently one of the important tasks of secondary schools. In fact, the management of vocational education activities for students in secondary schools of Thap Muoi district, Dong Thap province, although it has achieved initial results, still has many problems. many difficulties and shortcomings. Based on the theoretical basis of vocational education and the current state of management, the article proposes some measures to manage vocational education activities for students in secondary schools of Thap Muoi district, Dong Thap province.