Rhodomyrtus tomentosa (Aiton) Hassk is a plant species belonging to the family Myrtaceae. It is widely distributed and used as a rich-nutrient food and a traditional medicine in South and East South Asia such as China, Thailand, Malaysia, and Vietnam. In Vietnam, the leaf, root, and fruits of R. tomentosa have been used to nourish the blood system, against diarrhoea, cure stomach ailments, antiinflammatory. The fruits of this plant are processed into wine, candy, syrup… The objective of the present study was to investigate the phytochemical constituents of the methanol extract of the seeds of R. tomentosa using gas chromatography–mass spectrometry (GC-MS). There were 31 phytochemicals detected in the methanol extract of Rhodomyrtus tomentosa seeds, including: fatty acids and their esters (38.65%)
pyrrogallols (23.43%)
terpenes, sterols and other aroma compounds. A variety of bioactive compounds was present in the seeds of R. tomentosa such as 1,2,3-Benzenetriol (22.33%), 9,12-Octadecadienoic acid (Z,Z)- (19.87%), n-Hexadecanoic acid (8.09%), Octadecanoic acid (2.96%), Vitamine E (2.94%), γ-Tocopherol (0.89%), γSitosterol (2.03%), Amyrin (1.78%), Cymene(1.45%), 5-Hydroxymethylfurfural (0.86%)…, which possessed the ability to be antioxidant, antiinfectious, antiinflammatory, anticancer, antifungal, antiviral and antibacterial, hypoglycemic, lipid-lowering, fat-reducing... This is the basis for developing applied research using the extract of Rhodomyrtus tomentosa seeds in daily life as well as improving the economic value of wild Rhodomyrtus tomentosa trees in Phu Quoc island district, Kien Giang province.