The concept of sustainability has been widely accepted in tourism to minimize the adverse effects of tourism. This study aims to develop a comprehensive set of indicators to help assess progress toward sustainable tourism for development in Kien Giang, Vietnam. Research to build and validate a set of indicators to measure sustainable tourism development, including economic, environmental, socio-cultural, infrastructure, technological, and political aspects. The indicator is helpful in providing a quantitative assessment of the tourist destination, identifying key intervention priorities, and identifying areas that need to be restructured. The indicator is applied to Kien Giang destinations in Vietnam, and the results are used as a guide for tourism planning. The conclusions of this study can be extrapolated to the study of other tourist destinations.