This study involved 228 teachers assigned to public elementary schools in the Division of Zambales, Subic District, Philippines, during the SY 2020 - 2021 and focused on the profile, experiences in the work-from-home setting as encountered by teachers, their coping mechanisms, as well as their work performance. The methodology of the study employed a descriptive correlation design. Statistical treatment includes frequency, percentage, mean, Analysis of Variance, and Pearson r. Findings revealed that teachers have highly experienced difficulties in the work-from-home setting, have very highly drawn coping mechanisms to overcome difficulties, and have a very satisfactory teaching performance. It is recommended that school administrators update teachers’ profiles, motivate teachers to undergo professional development through enrolling in graduate schools, help teachers with difficulties encountered in the work-from-home setting in the new normal through peer mentoring, motivate teachers to practice coping mechanisms and re-evaluate the work performance of teachers. Finally, teachers should learn to cope up with the challenges and difficulties in the work-from-home settings to have an outstanding work performance.