Đặc điểm vi phẫu, hoạt tính chống oxy hóa và ức chế enzym α-Glucosidase của các cao chiết cây muống biển (Ipomoea pes

Đặc điểm vi phẫu, hoạt tính chống oxy hóa và ức chế enzym α-Glucosidase của các cao chiết cây muống biển (Ipomoea pes - caprae)

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Tác giả: Thị Lệ Lý, Hữu Phúc và Phạm Thành Trọng Nguyễn, Thị Yến Nhi Nguyễn, Kim Ngọc Trì

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu khoa học và Phát triển kinh tế, 2023

Mô tả vật lý: tr.221-231

Bộ sưu tập: Metadata

ID: 380513

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Cây Muống biển (Ipomoea pes - caprae) là loài cây hoang dại, mọc nhiều trên bãi biển ở một số nước vùng Đông Nam Á nên nguyên liệu phong phú, dễ tìm. Nghiên cứu về loài Muống biển hiện nay còn hạn chế ở một số bộ phận như hoa, quả, hạt, rễ cho thấy tiềm năng chống oxy hóa tốt. Đề tài được thực hiện nhằm khảo sát đặc điểm vi phẫu, thành phần hóa học và một số hoạt tính sinh học của các loại cao chiết cây Muống biển, cung cấp cơ sở cho các nghiên cứu tiếp theo cho việc sử dụng như một cây dược liệu. Kết quả nghiên cứu cho thấy vi phẫu lá có biểu bì trên, mô dày, libe, gỗ và biểu bì dưới. Vi phẫu thân có biểu bì, mô dày phiến, mô mềm, mô cứng, libe, gỗ và mô mềm đạo. Thành phần hóa học chính của cây là polyphenol, carotenoid, anthraquinon, saponin, tanin, hợp chất polyuronic. Thử nghiệm loại gốc tự do DPPH cho thấy hoạt tính chống oxy hóa của cao ethanol 50% là cao nhất với IC50 = 7,95 ± 0,35 µg/mL. Các cao chiết cũng thể hiện hoạt tính ức chế α-glucosidase khá mạnh trong đó cao nước là mạnh nhất với IC50 =7,92 ± 0,05 µg/mL. Riêng cao chiết ethanol 96% có hoạt tính ức chế α-glucosidase không đáng kể.Ipomoea pes - caprae is a wild plant grown on beaches in Southeast Asian countries so they are easy to find. Currently, only some parts such as flowers, fruits, seeds, and roots of Ipomoea pes - caprae have been studied to show quite good antioxidant potential. The study aimed to investigate the microsurgical characteristics, chemical composition and some biological activities of Ipomoea pes - caprae extracts. Research results showed that leaf microsurgery has an upper epidermis, thick tissue, libe, wood and lower epidermis. Body microsurgery has epidermis, lamina propria, soft tissue, hard tissue, libe, wood and soft tissue. The main chemical components of Ipomoea pes - caprae are polyphenols, carotenoids, anthraquinones, saponins, tannins, polyuronic compounds. The DPPH free radical scavenging test showed that the antioxidant activity of 50% ethanol extract was the highest with IC50 = 7.95 ± 0.35 µg/mL. The extracts also showed strong α-glucosidase inhibitory activity in which aqueous extract was the strongest with IC50 = 7.92 ± 0.05 µg/mL. However, the 96% ethanol extract had negligible α-glucosidase inhibitory activity.

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