Thành phần hóa học của cây lăn tăn

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Tác giả: Văn Phúc Đinh, Thị Thùy Vân Hồ, Bùi Linh Chi Huỳnh, Kim Phi Phụng Nguyễn, Nguyễn Kim Tuyến Phạm, Thị Khánh Linh Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học Trường Đại học Quy Nhơn, 2024

Mô tả vật lý: tr.9

Bộ sưu tập: Metadata

ID: 380553

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Chi Pilea là chi lớn nhất của họ Urticaceae, bao gồm hơn 600 loài. Pilea được mô tả lần đầu tiên bởi nhóm tác giả Lindley năm 1821 và Weddell năm 1869 và có thể dễ dàng phân biệt với các các chi khác trong họ Urticaceae bằng sự kết hợp của các lá mọc đối, các lá kèm trong cuống lá có dây chằng ở mỗi nách lá. Dựa vào hình thái rìa lá, 159 loài của chi Pilea đã được định danh và phân thành 3 nhóm: Integrifoliae, Heterophyllae và Dentatae. Killip vào năm 1936 chia Pilea thành 12 nhóm chủ yếu dựa trên nghiên cứu của Weddell vào năm 1856, 1869. Hầu hết các loài là các loại thảo mộc nhỏ, nhiều trong số đó là thực vật biểu sinh. Từcao chloroform và cao acetone của cây Lăn tăn(Pilea microphylla) đã phân lập được bảy hợp chất tinh khiết, bao gồm ergosterol (1), β-sitosterol (2), daucosterol (3), isoarborinyl acetate (4), 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (5), 3,5,7-trihydroxy-8-methoxyflavone (6) và kaempferol (7). Cấu trúc hóa học của các hợp chất được xác định dựa trên các phương pháp hóa lý hiện đại như phổ HR-ESI-MS, 1D và 2D-NMR và so sánh với tài liệu tham khảo. Tất cả bảy hợp chất này lần đầu tiên được cô lập từ chi Pilea.Pilea, the largest genus of the Urticaceae, included over 600 species. This genus, first described by Lindley in 1821 and Weddell in 1869, is easily distinguished from other Neotropical Urticaceae by the combination of opposite leaves and ligulate intrapetiolar stipules in each leaf axil. Based on the isomorphy and margin morphology of the leaf 159 species were recognized and classified into three groups: Integrifoliae, Heterophyllae, and Dentatae. Killip in 1936 subdivided Pilea into 12 groups largely based on Weddell’s studies in 1856, 1869. Most of the species are small herbs, many of which are facultatively epiphytic or epipetric.Phytochemical investigations ofthe chloroform and acetone extracts of the whole plant Pilea microphylla led to the isolation of seven pure compounds, including ergosterol (1), β-sitosterol (2), daucosterol (3), isoarborinyl acetate (4), 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (5), 3,5,7-trihydroxy-8-methoxyflavone (6), and kaempferol (7). Their chemical structures were elucidated by extensive HR-ESI-MS, 1D and 2D-NMR spectroscopic data analysis, and comparison with previously published ones. Seven compounds were reported for the first time from Pilea genus.

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