In the aim of further research of the highly bioactive benzofuran and triazine derivatives, the synthesis of 1,2,4-triazine derivatives bearing the benzofuran moiety has been undertaken. Using a simple and convenient method, a three steps synthesis of novel functionalized 1,2,4-triazine derivatives from readily available starting materials has been described. Herein, two derivatives of 1,2,4-triazine were obtained in moderate yields. The structures of all synthesized compounds were elucidated by spectral methods of analysis