Objectives: To assess the quality of life among patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023. Research participants and methods:Cross-sectional descriptive study was conducted with 200 patients from March 2023 to June 2023. The Quality of Life in Reflux and Dyspepsia patients (QOLRAD) was used to interview patients for gastrointestinal examination and endoscopy at Tuyen Quang General Hospital. Results: The average quality of life score among patients was 4.33 - 4.46. In which all fields were at a good level, not too different from the bad level, the average score in the item eating/drinking (4.33), the items of sleep disorders (4.36), the item of emotion (4.39), the item of physical/social (4.39), vitality domain (4.46). Conclusion:The quality of life of patients with gastroesophageal reflux disease at Tuyen Quang General Hospital in 2023 is at a good level in all items