Entrepreneurship and innovation are meaningful activities for students, helping to improve their own income and reduce their efforts to work for the society. Along with the rapid development of science and technology, students’ entrepreneurship and innovation activities need to be paid attention and timely orientation, helping them to eliminate difficulties and promote their potential capital. has to up to the public. This study assesses the current status of entrepreneurship and innovation activities of students at Can Tho University of Engineering and Technology. From the results of the research, a number of design solutions are proposed and applied in a timely manner, contributing to improving the efficiency of this activity in the coming time.