This article presents the results of evaluating the service quality of library in Dong Thap University, which are based on the feedback of 232 students who are studying at the university and are directly using the library services. By using the Exploratory Factor Analysis method (EFA) and linear regression analysis methods, the study identifies four factors that affect the quality of library service and their impact level, including (1) Facilities of library, (2) Capacity of librarian, (3) Response of library, and (4) Reliability of library. In particular, the two factors that have a strong influence on the quality of library services are the library facilities and the library’s responsibility. In addition, the study also points out two observed variables corresponding to two contents of service quality which are meant to explain well to each factor. These are the major factors that greatly affect the quality of library services in Dong Thap University.