Tính hợp lý trong sử dụng thuốc ức chế bơm proton (PPI)

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Tác giả: Đặng Minh Trí Bùi, Đặng Phương Chi Bùi, Hồng Ngọc Nguyễn

Ngôn ngữ: Vie

Ký hiệu phân loại: 615 Pharmacology and therapeutics

Thông tin xuất bản: Y học cộng đồng 2021

Mô tả vật lý: 68-71

Bộ sưu tập: Metadata

ID: 395674

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Khảo sát tính hợp lý trong sử dụng thuốc ức chế bơm proton (PPI) tạiBệnh viện Quân y 120 tỉnh Tiền Giang.Đối tượng và phương pháp:Nghiên cứu mô tả cắt ngang trên 4532 đơn thuốc khám bệnh ngoại trú của bệnh nhân được bác sĩ kê đơn thuốc từ ngày 01/7/2020 đến ngày 30/7/2020 tại các phòng khám thuộc khoa Khám bệnh - Bệnh viện Quân y 120.Kết quả:Tỷ lệ chỉ định thuốc ức chế bơm proton chưa an toàn chiếm 12,13%. Tỷ lệ đơn thuốc không có hướng dẫn thời gian sử dụng thuốc ức chế bơm proton (0,79%). Tỷ lệ đơn thuốc có tương tác thuốc là 52,14%, clopidogrel là thuốc tương tác được sử dụng chung với PPI nhiều nhất (48,3%). Tỷ lệ có chỉ định thuốc ức chế bơm proton chưa hợp lý là: 9,76%. Tỷ lệ đơn thuốc có chỉ định thuốc ức chế bơm proton điều trị viêm dạ dày chiếm 66,14% so với tổng đơn thuốc có thuốc ức chế bơm proton chưa hợp lý.Kết luận:Tỷ lệ thuốc ức chế bơm proton chưa an toàn, chưa hợp lý, đơn thuốc không có hướng dẫn thời gian sử dụng thuốc ức chế bơm proton chiếm tỷ lệ thấp. Tỷ lệ đơn thuốc có tương tác chiếm tỷ lệ cao, clopidogrel là thuốc tương tác được sử dụng chung với PPI nhiều nhất. Đơn thuốc chưa hợp lý trong sử dụng PPI chủ yếu là bệnh viêm dạ dày., Tóm tắt tiếng anh, To investigate the reasonableness of using proton pump inhibitors (PPI) at 120 Military Hospital in Tien Giang province. Subjects and methods: Cross-sectional descriptive study on 4532 outpatient prescriptions of patients who were prescribed drugs by doctors from July 1st, 2020 to July 30th, 2020 at clinics of the examination department - Military Hospital 120.Results: Prescribing unsafe proton pump inhibitors accounted for 12.13%. Percentage of prescriptions without instructions for use of proton pump inhibitors (0.79%). The proportion of prescription drugs with drug interactions was 52.14%, clopidogrel was the most interactive drug commonly used with PPIs (48.3%). The proportion of proton pump inhibitors indicated unreasonable was 9.76%. The proportion of prescriptions with proton pump inhibitors for gastritis treatment accounted for 66.14% of the total number of prescriptions with proton pump inhibitors that were not reasonable. Conclusion: The proportion of proton pump inhibitors was not safe and reasonable and the proportion of prescription drugs with no instructions on how long to use proton pump inhibitors were low. The proportion of prescription interacting drugs accounted for a high proportion, clopidogrel was the most interactive drug commonly used with PPIs. Unreasonable prescriptions in PPI used mainly gastritis.

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