Sự phù hợp trong sử dụng thuốc điều trị bệnh tay chân miệng

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Tác giả: Đặng Lan Hương Bùi, Đặng Phương Chi Bùi, Thị Kiều Trinh Trần

Ngôn ngữ: Vie

Ký hiệu phân loại: 615 Pharmacology and therapeutics

Thông tin xuất bản: Y học cộng đồng 2021

Mô tả vật lý: 51-57

Bộ sưu tập: Metadata

ID: 399154

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Đánh giá sự phù hợp trong sử dụng thuốc điều trị bệnh tay chân miệng tại Bệnh viện Nhi đồng thành phố Cần Thơ năm 2019.Nghiên cứu mô tả cắt ngang hồi cứu trên 400 hồ sơ bệnh án của các bệnh nhân điều trị nội trú tại Bệnh viện Nhi Đồng Cần Thơ trong thời gian 1/2019 đến tháng 12/2019.Nhóm bệnh nhân sử dụng liều phù hợp với liêu quy định có sự khác biệt có ý nghĩa với nhóm bệnh nhân sử dụng liều chưa phù hợp có ý nghĩa thống kê (P = 0.000 <
0.005). Thuốc có nhịp đưa thuốc phù hợp nhiều nhất là Paracetamol, Midazolam, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G, Cefuroxim với 100% theo đúng khuyến cáo. Trong đó phù hợp với khuyến cáo thấp nhất là Cefotaxim (89,9%) và Ceftriaxon (83.3%). Thuốc đường uống được sử dụng nhiều nhất: Paracetamol, Ibuprofen, Phenobarbital, Clorpheniramin, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G phù hợp vơi khuyến cáo 100%. Tỷ lệ phù hợp so với khuyến cáo thấp nhất là thuốc Cefuroxim chiếm 6,7% sử dụng đường tiêm phù hợp vơi khuyến cáo. Cặp tương tác gặp nhiều hơn là Paracetamol dùng đồng thời với Phenobabital ở mức độ trung bình chiếm tỷ lệ 90,6% tổng 149 số tương tác ghi nhận được và chiếm tỷ lệ thấp hơn là cặp Midazolam với Phenobabital chiếm 9,4%.Hầu hết các thuốc có chỉ định sử dụng phù hợp cao, trong đó cao nhất là các thuốc Paracetamol, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G. Các thuốc kháng sinh có tỷ lệ sử dụng phù hợp thấp nhất., Tóm tắt tiếng anh, To evaluate the appropriateness in using drugs of hand, foot and mouth disease treatment at the Children's Hospital of Can Tho city in 2019.Retrospective cross-sectional descriptive study on 400 medical records of inpatients at Can Tho Children's Hospital during the period from January 2019 to December 2019.There was a statistically significant difference between the group of patients using the dose appropriate to the prescribed dose (P = 0.000 <
0.005). Drugs with the most suitable delivery rhythm were Paracetamol, Midazolam, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G, Cefuroxim with 100% as recommended. The lowest rate of used drugs compared to the recommendations was Cefotaxim (89.9%) and Ceftriaxon (83.3%). The most used oral medications: Paracetamol, Ibuprofen, Phenobarbital, Chlorpheniramine, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G were suitable to the 100% recommendation. The lowest appropriate rate compared with the recommendation was Cefuroxime, which accounted for 6.7%, using the injection route in accordance with the recommendation. The more common pair of interactions was Paracetamol and Phenobabital concomitantly accounted for 90.6% of the total 149 of the recorded interactions and a lower proportion was the pair of Midazolam with Phenobabital, accounting for 9.4%.Most drugs with highly suitable indications for use, of which the highest were Paracetamol, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G. Antibiotics had the lowest appropriate utilization rate.

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