Thực trạng và nguyên nhân sử dụng kháng sinh trong điều trị viêm tiểu phế quản trẻ em

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Tác giả: Thị Thảo Đỗ, Thị Minh Hương Lê, Thị Tâm Nguyễn, Hà Phương Võ

Ngôn ngữ: Vie

Ký hiệu phân loại:

Thông tin xuất bản: Nhi khoa 2023

Mô tả vật lý: 48-54

Bộ sưu tập: Metadata

ID: 401581

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Tóm tắt
Chủ đề

Nghiên cứu mô tả loạt ca bệnh VTPQ được điều trị nội trú tại khoa nhi Bệnh viện Vinmec Times City từ tháng 01/2022 đến tháng 12/2022. Tất cả bệnh nhân được đánh giá lâm sàng, xét nghiệm công thức máu, CRP, xét nghiệm dịch tỵ hầu tìm virut và vi khuẩn và ghi nhận các trường hợp dùng kháng sinh, phân tích lý do bệnh nhân phải dùng kháng sinh trong quá trình điều trị.Kết quả: Có 68 bệnh nhân VTPQ, tuổi trung bình là 9,2 + 5,4 tháng, nam/nữlà 1,5. Tỉ lệ sử dụng kháng sinh chiếm 51.5%, kháng sinh chủ yếu là Amoxicillin kết hợp Clavulamox chiếm 60%, đường dùng chủ yếu là tĩnh mạch chiếm 62.9%, thời gian trung bình dùng kháng sinh trong mỗi đợt nằm nội trú là 5,20 ± 1,43 ngày. Lí do chủ yếu quyết định việc dùng kháng sinh là xét nghiệm máu có bằng chứng viêm và kết quả nuôi cấy dịch tỵ hầu có mọc vi khuẩn với tỉ lệ lần lượt là 31,4% và 40,0%.Kết luận: Tỷ lệ sửdụng kháng sinh trong điều trị VTPQ chiếm 51,5%, cơ sở đề sửdụng kháng sinh là lâm sàng phổi có rale ầm, mức độ nặng vừa, chỉ số viêm trong máu cao và có bằng chứng vi khuẩn trong dịch tỵ hầu và hình ảnh X-quang phổi có đám mờ., Tóm tắt tiếng anh, This research recruited all bronchiolitis inpatients in Vinmec Timescity International Hospital from Jan 2022 to Dec 2022. The reason of antibiotic application was analysed based on clinical symptoms, complete blood count, CRP, nasopharyngeal test for virus and bacteria.Result: There were 68 inpateints acquiring bronchiolitis, with mean age 9,2 ± 5,4 months and male/female ratio was 1,5. Among them, the children who were prescribed antibiotics took up 51.5%.The most common drug choice was Amoxicillin-Acidclavulanic, accounting for 60%. The primary route of administration was intravenous, 62.9%. Average duration of antibiotic using was 5,20 ± 1,43 days. The explaination for antibiotic administration was elevatedinflammatory biomarkers (in 31,4% cases) and positive nasopharyngeal culture (in 40% cases).Conclusion: The rate of administering antibiotics in bronchiolitis treatment in Vinmec Timescity International Hospital was 51.5%.The justification forantibiotic using was clinical symptome, elevated inflammatory biomarkers, positive nasopharyngeal culture and X-ray.

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