Objective: To assess the initial outcomes of the technical application and treatment of inguinal hernia (IH) using transabdominal preperitoneal laparoscopy (TAPP) with a grip self-fixating mesh at Hai Phong University Hospital from January 2022 to December 2023. Patients and Methods: This study included 30 patients diagnosed with IH who were treated with TAPP at the Hai Phong Medical University Hospital from January 2022 to December 2023. Results: The mean age was 54.5 ± 12.1 years. Of these, 58.4% were aged <
60 years. There were 19 (63.3%) had right-sided IH and 11 (36.7%) had left-sided IH. Indirect IH was observed in 23/30 patients. The mean operation time was 87.3 ± 12.7 minutes. The mean postoperative pain duration was 3.1 ± 1.5 days. The mean length of hospital stay was 5.76 ± 1.17 days, the shortest was 3 days, and the longest was 9 days. The mean time to return to normal activities was 1.3 ± 0.5 days. Four of the 30 patients experienced postoperative complications, including one patient with wound infection, one patient with urinary retention, and two patients with thigh numbness. Conclusion: TAPP with grip self-fixating mesh for IH yielded good outcomes and rapid postoperative recovery.