Liên quan giữa chỉ số đề kháng insulin với một số đặc điểm chuyển hóa ở bệnh nhân đái tháo đường típ 2

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Tác giả: Thị Trang Lê, Đức Kỷ Ngô, Thị Hà² Nguyễn

Ngôn ngữ: Vie

Ký hiệu phân loại: 616.4 Diseases of hematopoietic, lymphatic, glandular systems Diseases of endocrine system

Thông tin xuất bản: Tạp chí Nội tiết và Đái tháo đường 2021

Mô tả vật lý: 46-50

Bộ sưu tập: Metadata

ID: 403325

Thêm vào giỏ Liên kết toàn văn

Nghiên cứu mối liên quan giữa đề kháng insulin với các đặc điểm chuyển hóa ở bệnh nhân đái tháo đường típ 2. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang 105 đối tượng đủ tiêu chuẩn chẩn đoán đái tháo đường típ 2 đang điều trị nội trú tại khoa Nội tiết - Đái tháo đường, Bệnh viện hữu nghị đa khoa Nghệ An, thời gian từ tháng 01/2021 - 04/2021. Kết quả nghiên cứu: tất cả 105 bệnh nhân đái tháo đường típ 2, trong đó nam chiếm tỷ lệ 54,3%, nữ chiếm tỷ lệ 45,7%. Tuổi trung bình của nghiên cứu là 66,82 ± 12,6 tuổi. Chỉ số HOMA1-IR là 6,90 ± 4,43. Có mối tương quan thuận có ý nghĩa thống kê giữa HOMA1-IR với các chỉ số vòng bụng (r = 0,286
p <
0,05), tỷ lệ vòng bụng/vòng hông (r = 0,221
p <
0,05) và chỉ số BMI (r = 296
p <
0,05). Có có mối tương quan thuận có ý nghĩa thống kê giữa HOMA1-IR với cholesterol (r = 0,229
p <
0,05) và LDL-cholesterol (r = 0,206
p <
0,05). Ngược lại có mối tương quan nghịch giữa HOMA1-IR với HDL-cholesterol (r = - 0,225
p <
0,05). Kết luận: Có mối tương quan giữa chỉ số đề kháng insulin HOMA1-IR với các chỉ số nhân trắc và một số các thành phần lipid máu ở bệnh nhân đái tháo đường típ 2., Tóm tắt tiếng anh, To study the relationship between insulin resistance and metabolic characteristics in patients with type 2 diabetes. Methods: A cross-sectional descriptive study of 105 subjects who met the criteria for diagnosis of type 2 diabetes and were undergoing inpatient treatment at the Department of Endocrinology and Diabetes, Nghe An General freinship Hospital. period from January 2021 to April 2021. Results: All 105 patients with type 2 diabetes, in which male accounted for 54.3%, female accounted for 45.7%. The mean age of the study was 66.82 ± 12.6 years old. The HOMA1-IR index is 6.90 ± 4.43. There was a statistically significant positive correlation between HOMA1-IR and waist circumference (r = 0.286
p <
0.05), waist/hip ratio (r = 0.221
p <
0.05) and BMI (r = 296
p <
0.05). There was a statistically significant positive correlation between HOMA1-IR with cholesterol (r = 0.229
p <
0.05) and LDL-cholesterol (r = 0.206
p <
0.05). In contrast, there is a negative correlation between HOMA1-IR and HDL cholesterol (r = - 0.225
p <
0.05). Conclusion: There is a correlation between the HOMA1-IR insulin resistance index with anthropometric indices and some blood lipid components in patients with type 2 diabetes

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