The purpose of the study is to test the awareness and prove the feasibility of applying the Theory of Multiple Intelligences to improve the quality of teaching the subject "Revolutionary Line of the Vietnamese Communist Party" in classes with large numbers of students at Hanoi National University of Education. The questionnaire was designed which includes the perception and evaluation of 136 students on the subject's goals and on Theory of Multiple Intelligences (survey at Poli class K67.7 and Poli K67.9 at Room 109, Building C, Hanoi National University of Education). The reliability of the scale was conducted on SPSS 20.0 software. The research results show that the application of Theory of Multiple Intelligences (MI) by studying characteristics, classification of student groups, in combination with appropriate measures will help learners improve the quality and outcomes of learning the subject "Revolutionary Line of the Vietnamese Communist Party". In addition, the study also provides reference suggestions for lecturers at other educational institutions having similar class backgrounds and models.DOI: 10.18173/2354-1075.2019-0140