Đặc điểm lâm sàng và giải phẫu bệnh ung thư dạ dày người cao tuổi

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Tác giả: Việt Dũng Hoàng

Ngôn ngữ: Vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam) 2023

Mô tả vật lý: 152-156

Bộ sưu tập: Metadata

ID: 407048

Thêm vào giỏ Liên kết toàn văn

Tìm hiểu đặc điểm lâm sàng ung thư dạ dày (UTDD) ở người cao tuổi (NCT). Đối tượng và phương pháp: Mô tả hồi cứu đặc điểm lâm sàng UTDD ở NCT, từ tháng 01 năm 2011 đến tháng 12 năm 2020 được phẫu thuật tại bệnh viện Hữu Nghị. Kết quả: 204 bệnh nhân (BN)
Nam 167 (81,9%), Nữ 37 (18,1%). Tuổi trung bình 72,78 ± 6,72. Yếu tố nguy cơ và bệnh phối hợp: hút thuốc lá 40,2%
tăng huyết áp 45,6%
bệnh tim mạch 23,5%
bệnh hô hấp 14,2%
đái đường 12,3%
ASA-II 75%. Đặc điểm lâm sàng: đau thượng vị 80,4%
đầy bụng khó tiêu 74,5%
gầy sút cân 45,1%
thiếu máu 72,5%. Vị trí u 1/3 dưới 77,9%
1/3 trên 5,9%
1/3 giữa 4,9%
khác 11,3%
Kích thước u ≥ 5cm chiếm 55,4%. Giải phẫu bệnh (GPB): thể loét, sùi, thâm nhiễm: 42,6%
39,2% và 18,1%. UTBM tuyến ống 62,7%
nhẫn 13,2%
nhày 10,8%
nhú 7,8%. Biệt hóa vừa 37,7%, kém biệt hóa 34,8%
biệt hóa cao 26,5%. Độ xâm lấn T3, T4 66,2%. Giai đoạn III và IV 47,5%. Kết luận: BN cao tuổi bị UTDD thường gặp ở Nam giới, nhiều bệnh phối hợp, triệu chứng hay gặp là đau bụng, ăn uống khó tiêu. Khối u chủ yếu ở 1/3 dưới
thường gặp UTBM tuyến ống, thể loét, độ biệt hóa vừa. Bệnh ở giai đoạn muộn vẫn chiếm tỷ lệ cao., Tóm tắt tiếng anh, To evaluate the Clinicopathologic Characteristics of gastric cancer in the elderly. Subject and Method: A study about Clinicopathologic Characteristics of gastric cancer in elderly who were operated with gastrectomies from January 2011 to December 2020 at Friendship Hospital. Result: in 204 patients with 167 (81.9%) males and 37 (18.1%) females
female/male ratio: 1/4.5
mean age: 72.7 ± 6.5. Risk factors and associated: smoking 40.2%: hypertension 45,6%
cardiovascular diseases 23.5%
respiratory diseases 14.2%
diabetes 12.3%
ASA-II 75%. Clinical features: abdominal pain 80.4%
dyspepsia 74.5%
weight loss 45.1%
anemia 72.5%. Location of carcinomas in the lower one-third, upper third and middle third: 77.9%
5.9%
4.0%
other site 11.3%. Tumor size ≥ 5cm: 55.4%. Macroscopic lesion: ulcerated, protruded and diffusely infiltrating ulceration type: 42.6%
39.2% and 18.1%. Moderately differentiated
poorly differentiated and well differentiated: 37.7%, 34.8% and 26.5%. Adenocarcinoma 62.7%
signet-ring cell carcinoma 13.2%
mucinous adenocarcinoma 10.8%
papillary adenocarcinoma 7.8%. Depth of invasion T3 and T4: 66.2%. TNM Stage III and IV: 47.5%. Conclusion: These results indicate that, gastric carcinoma in elderly patients showed predominantly males with more comorbidities. Main symptoms of abdominal pain and dyspepsia. Predominance of tumor in the lower one-third with ulcerated and moderately differentiated type. The advanced stage still is high.

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