Tình hình sử dụng thuốc điều trị tăng huyết áp ở bệnh nhân suy thận giai đoạn IV

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Tác giả: , Tùng Hiệp Bùi, Văn Mã Đỗ, Hùng Duy Hậu Phan

Ngôn ngữ: Vie

Ký hiệu phân loại:

Thông tin xuất bản: Y học cộng đồng 2021

Mô tả vật lý: 35-40

Bộ sưu tập: Metadata

ID: 407170

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Khảo sát tình hình sử dụng thuốc trong kê đơn điều trị tăng huyết áp ở bệnh nhân suy thận mạn giai đoạn IV tại Bệnh viện đa khoa An Sinh. Nghiên cứu hồi cứu, mô tả cắt ngang trên 153 bệnh án của các bệnh nhân (BN) được chẩn đoán tăng huyết áp (THA) có kèm suy thận mạn giai đoạn IV đã được điều trị tại khoa Nội thận - Lọc máu Bệnh viện đa khoa An Sinh, thành phố Hồ Chí Minh, từ tháng 01/06/2019 đến 31/05/2020. Thuốc ức chế men chuyển (ƯCMC) và thuốc ức chế calci là hai nhóm thuốc được dùng phổ biến nhất. Nhóm ức chế adrenergic và nhóm lợi tiểu được dùng ít hơn, nhóm chẹn thụ thể angiotensin (CTTA) được dùng ít nhất. 75,82% BN phải sử dụng phác đồ phối hợp thuốc
trong đó phác đồ phối hợp 2 thuốc và 3 thuốc được sử dụng nhiều nhất. Cặp phối hợp thường gặp trong mẫu khảo sát trong phác đồ phối hợp 2 thuốc là ƯCMC và lợi tiểu, sau đó là ƯCMC và ức chế calci. Với cặp phối hợp 3 nhóm thuốc thì phối hợp thường gặp là ƯCMC, ức chế calci và ức chế adrenergic. Nhóm thuốc ƯCMC và chẹn kênh calci được sử dụng chủ yếu. Phác đồ phối 2 và 3 thuốc chiếm tỷ lệ cao, trong đó chủ yếu là phối hợp thuốc ƯCMC với lợi tiểu và ƯCMC với chẹn kênh calci với ức chế adrenergic., Tóm tắt tiếng anh, To investigate the use of drugs in prescribing for treatment of hypertension in patients with stage IV chronic renal failure at An Sinh General Hospital. Study of retrospective, cross-sectional description of 153 medical records of patients diagnosed with hypertension with stage IV chronic renal failure who were treated in the Department of Endocrinology - Dialysis of An Sinh General Hospital, Ho Chi Minh City, from June 1st, 2019 to May 31st, 2020. ACE inhibitors and calcium inhibitors were the two most commonly used groups of drugs. The adrenergic blocker group and the diuretic group were used less common, the Angiotensin receptor inhibitors (ARI) used the least. 75.82% of patients must use the combination regimen
in which the combination regimen of 2 drugs and 3 drugs was used the most. The most common combination pair seen in the sample in a two-drug combination regimen were ACE inhibitors and diuretics, followed by ACE inhibitors and calcium inhibitors. With a combination of 3 drug groups, the most common combination was ACE inhibitors, calcium inhibitors and adrenergic inhibitors. Conclusion: ACE inhibitors and calcium channel blockers were mainly used. Combination regimen of 2 and 3 drugs accounted for a high proportion, in which the combination of ACE inhibitors with diuretics and ACE inhibitors with calcium channel blockers and adrenergic inhibitors were mainly used.

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