Đặc điểm lâm sàng và vi sinh ở bệnh nhân viêm nội tâm mạc nhiễm khuẩn do staphylococcus aureus

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Tác giả: Văn Sỹ Hoàng, Công Duy Trần

Ngôn ngữ: Vie

Ký hiệu phân loại: 616 Diseases

Thông tin xuất bản: Tạp chí Y học Việt Nam 2023

Mô tả vật lý: 29-33

Bộ sưu tập: Metadata

ID: 407753

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Tóm tắt
Chủ đề

Khảo sát đặc điểm lâm sàng và vi sinh của bệnh nhân VNTMNK do Staphylococcus aureus (S.aureus). Đối tượng và phương pháp nghiên cứu: hồi cứu, cắt ngang mô tả ở các bệnh nhân VNTMNK do S.aureus điều trị nội trú tại Bệnh viện Chợ Rẫy từ 01/2015 đến 12/2019. Kết quả: Trong giai đoạn 5 năm (2015-2019), 39 bệnh nhân VNTMNK do S.aureus nhập bệnh viện Chợ Rẫy. Tuổi trung bình của bệnh nhân là 42,9±18,2 và nam chiếm 53,9%. VNTMNK do S.aureus xảy ra ở 69,2% bệnh van tim tự nhiên
10,3% van tim nhân tạo
5,1% bệnh tim bẩm sinh và 15,4% không có tiền sử bệnh tim mạch. Đường vào phổ biến nhất của tác nhân gây bệnh là qua da (23,1%). Triệu chứng lâm sàng thường gặp nhất ở bệnh nhân VNTMNK do S.aureus là sốt (92,3%) với thời gian sốt trung bình trước nhập viện là 13,5 ngày. Tỉ lệ vi khuẩn S.aureus kháng methicillin (MRSA) là 64,1% và 100% S.aureus nhạy với kháng sinh vancomycin, teicoplanin, linezolid và tigecycline. Kết luận: VNMTNK do S.aureus có một số đặc điểm lâm sàng riêng biệt cần lưu ý trong chẩn đoán và tỉ lệ cao đề kháng với methicillin., Tóm tắt tiếng anh, To survey the clinical and microbiological characteristics of patients with S.aureus IE. Subjects and methods: This was a retrospective, cross-sectional and descriptive study performed on patients with S.aureus IE who were admitted to Cho Ray Hospital from January 2015 to December 2019. Results: In the five years (2015-2019), there were 39 hospitalized patients with S.aureus IE. The mean age of patients was 42.9±18.2 years and 53.9% were male. S.aureus IE occurred in 69.2% of patients with native valves
10.3% with prosthetic valves
5.1% with congenital heart disease, and 15.4% with no prior cardiovascular disease. The most common portal of entry is cutaneous (23.1%). The most frequent clinical symptom in S.aureus IE was fever (92.3%) and the mean pre-admission duration of fever was 13.5 days. The rate of methicillin-resistant S.aureus (MRSA) was 64.1% and 100% S.aureus were sensitive to vancomycin, teicoplanin, linezolid, and tigecycline. Conclusions: S.aureus IE has several special clinical characteristics that should be taken into consideration and the high rate of MRSA.

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