Viêm mao mạch dị ứng ở trẻ em tại Khoa Nhi, Bệnh viện Bạch Mai

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Tác giả: Văn Đếm Phạm

Ngôn ngữ: Vie

Ký hiệu phân loại: 618.92 Pediatrics

Thông tin xuất bản: VNU Journal of Science: Medical and Pharmaceutical Science, 2020

Mô tả vật lý: 91-97

Bộ sưu tập: Metadata

ID: 408048

Thêm vào giỏ Liên kết toàn văn

Viêm mạch dị ứng hay còn gọi là Henoch-Schonlein Purpura thường gặp ở trẻ em. Mục tiêu nghiên cứu: mô tả đặc điểm lâm sàng, cận lâm sàng của viêm mao mạch dị ứng ở trẻ em. Đối tượng nghiên cứu: trẻ được chẩn đoán viêm mao mạch dị ứng vào điều trị tại Khoa Nhi, Bệnh viện Bạch Mai trong thời gian từ tháng 01 năm 2017 đến hết tháng 12 năm 2018. Phương pháp nghiên cứu: mô tả loạt ca bệnh. Kết quả: tuổi trung bình khởi phát bệnh là 9,1 ± 3,2 tuổi. Tỷ lệ trẻ trai/trẻ gái là 1,17:1. Tỉ lệ bệnh khởi phát vào mùa đông xuân cao nhất (38%), 44% trường hợp có nhiễm trùng trước khi khởi phát bệnh. Triệu chứng lâm sàng gặp nhiều nhất là ban xuất huyết đối xứng 2 bên (90%), 68,0% có các biểu hiện tại cơ quan tiêu hóa, 18,0% có tổn thương thận. Kết quả điều trị: 78% trẻ khỏi hoàn toàn, 16% trẻ có tái phát, không thuyên giảm là 6%. Kết luận: Viêm mạch dị ứng có biểu hiện chính là các ban xuất huyết đối xứng, kèm theo triệu chứng tại đường tiêu hóa, tổn thương thận ít gặp hơn, tỉ lệ điều trị khỏi cao., Tóm tắt tiếng anh, Henoch-Schonlein Purpura (HSP) is one of the most common vasculitis disease in children. The main symtomps are rash, arthritis, abdominal pain, and kidney disease. In particular, kidney involvement is important to predict long-term outcomes of disease. Aim: This study aimed to describe the epidemic characteristics, clinical manifestations and some laboratory findings of HSP in children. Subjects of study: We studied 50 patients diagnosed with HSP at Deparment of Pediatrics, Bach Mai hospital from 2017 to 2018. Results: The mean age was 9,1 ± 3,2 years, with the ratio of male to female to be 1,17:1. HSP has seasonal characteristics, it was more common in the spring (43.4%) and the winter (26.1%). 44% of HSP cases were preceded by an acute infectious or allergic illness. The common clinical manifestation was reddish-purple spots such as the sock (90%) and digestive tract symptoms (68%), nephritis (18%). At the end of research, 78% of cases was complete remission, 16% of cases relapse and 6% non response. Conclusion: The common clinical manifestation was reddish-purple spots such as the sock and digestive tract symptoms. Out come of HSP was high complete remission rate.

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