Chất lượng cuộc sống và các yếu tố liên quan của bệnh nhân Pemphigus thông thường

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Tác giả: Thị Minh Phương Phạm, Thị Thảo Phạm, Thị Hà Giang Quách

Ngôn ngữ: Vie

Ký hiệu phân loại: 616.5 Diseases of integument

Thông tin xuất bản: Da liễu học Việt Nam 2023

Mô tả vật lý: 72-81

Bộ sưu tập: Metadata

ID: 408668

Thêm vào giỏ Liên kết toàn văn

Pemphigus là bệnh da bọng nước tự miễn gây ra bởi các kháng thể chống lại desmoglein, đặc trưng bởi sự xuất hiện của các bọng nước cùng các vết trợt đau trên da và niêm mạc. Bệnh có ảnh hưởng rất lớn đến chất lượng cuộc sống của bệnh nhân. Mục tiêu: Đánh giá chất lượng cuộc sống (CLCS) của bệnh nhân pemphigus thông thường điều trị ngoại trú tại Bệnh viện Da liễu Trung ương, đồng thời xác định các yếu tố liên quan đến CLCS của bệnh nhân pemphigus thông thường. Phương pháp: Nghiên cứu mô tả cắt ngang trên 70 bệnh nhân bị pemphigus thông thường điều trị ngoại trú tại tại Bệnh viện Da liễu Trung ương từ tháng 10/2020 đến tháng 12/2020 đáp ứng đủ tiêu chuẩn được lựa chọn vào nghiên cứu. CLCS của bệnh nhân được đánh giá bằng bảng câu hỏi DLQI, mức độ ảnh hưởng đời sống tinh thần của bệnh nhân được đánh giá bằng bộ câu hỏi GHQ - 12, mức độ nặng của bệnh nhân được đánh giá bằng chỉ số PDAI. Chương trình SPSS 20.0 được sử dụng để phân tích số liệu. Kết quả: Điểm DLQI trung bình của 70 bệnh nhân trong nghiên cứu của chúng tôi là 9,4 ± 7,2. 47,1% bệnh nhân có GHQ - 12 (+), điều này có nghĩa là bệnh nhân có các rối loạn tâm thần ở mức độ nhẹ như lo lắng hoặc trầm cảm. CLCS của bệnh nhân có liên quan đến triệu chứng cơ năng, tổn thương niêm mạc, mức độ nặng của bệnh và liều corticoid đang dùng. Có mối tương quan đồng biến giữa điểm DLQI và điểm GHQ - 12 của bệnh nhân., Tóm tắt tiếng anh, Pemphigus is an autoimmune bullous disease caused by autoantibodies directed against desmogleins, and it is clinically characterized by bullae and painful erosions of the skin and mucous membranes. Pemphigus has a strong effect on patients' quality of life. To evaluate quality of life and related factors in patients with pemphigus vulgaris that were treated in the Out - patient Department at the National Hospital of Dermatology. A cross - sectional descriptive study on 70 out - patients with pemphigus vulgaris at the National Hospital of Dermatology and Venereology from October 2020 to December 2020. The patient's quality of life was assessed by the DLQI questionnaire, the patient's mental status was assessed by the GHQ - 12 scale, and the patient's severity was assessed by the PDAI index. The program SPSS 20.0 was used to analyze the data. The average DLQI score of 70 patients in our study was 9,4 ± 7,2
47,1 percent of the patients showed a positive result in the GHQ - 12, reflecting probable minor psychiatric nonpsychotic conditions such as anxiety or depression. The DLQI score correlated with functional symptoms, mucosal lesions, disease severity, and corticosteroid dose. DLQI score positively correlated to the GHQ - 12 score.

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