Tầm quan trọng của giải phẫu bệnh trong ghép gan

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Huyên Đào, Thị Trang Lê, Thị Minh Hạnh Ngô

Ngôn ngữ: Vie

Ký hiệu phân loại: 616.025 Medical emergencies

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam) 2023

Mô tả vật lý: 188-196

Bộ sưu tập: Metadata

ID: 409757

Thêm vào giỏ Liên kết toàn văn

Tóm tắt
Chủ đề

Ghép mô và bộ phận cơ thể người nói chung và ghép gan nói riêng là một trong những thành tựu tiên tiến nhất của y học hiện đại. Ghép gan là một trong những phương pháp điều trị ngày càng được áp dụng rộng rãi để điều trị các bệnh lý gan, đặc biệt ở những bệnh gan giai đoạn muộn. Tuy nhiên, ghép gan có thể xảy ra nhiều biến chứng. Vai trò của bác sĩ Giải phẫu bệnh bắt đầu với việc đánh giá trước khi ghép gan của người nhận bằng cách chẩn đoán và xác định bệnh gan tiềm ẩn, đánh giá gan của người hiến tặng bằng việc xác định chất lượng gan cho có phù hợp với gan hiến tặng để cấy ghép. Việc đánh giá này được thực hiện trước hoặc trong khi phẫu thuật thông qua kỹ thuật sinh thiết tức thì. Vai trò của Giải phẫu bệnh tiếp tục đánh giá và theo dõi giai đoạn sau ghép, không chỉ đánh giá các bệnh liên quan đến mô ghép như thải ghép, bệnh gan nguyên phát tái phát, tác dụng phụ do thuốc ức chế miễn dịch mà còn đánh giá các mô tạng khác để tìm đặc điểm nhiễm trùng, bệnh ác tính.... Do đó, quản lý lâu dài bệnh nhân ghép gan không chỉ bảo tồn chức năng mảnh ghép mà còn phải phòng ngừa, điều trị biến chứng cũng như là sàng lọc bệnh ác tính. Vai trò của các nhà Giải phẫu bệnh đánh giá biến đổi mô học của mảnh gan ghép giúp cung cấp thêm dữ liệu cho các nhà lâm sàng, nhà gan mật để lựa chọn phương pháp điều trị thích hợp, chăm sóc bệnh nhân ghép gan được tối ưu và hiệu quả., Tóm tắt tiếng anh, Tissue and organ transplantation in general, liver transplantation in particular is one of the most advanced achievements of modern medicine. Liver transplantation is one of the more popular methods to treat liver diseases, especially final-stage ones. However, liver transplantation can result in complications. The role of pathologists begins with the assessment of the recipient's liver by diagnosing and identifying hidden liver diseases. Phathologists also make the assessment of the donor's liver if it is compatible for transplantation. This evaluation is conducted before or during operation with a liver frozen section. Pathology's role continues with the evaluation and monitoring during the post-transplant period, not only to evaluate liver allograft such as rejection, recurrence of primary liver diseases, and side effects due to immunosuppressive drugs. Pathologists also play an essential role in the evaluation of other organs to detect infectious and malignant diseases... Therefore, long-term management of patients with liver transplantation should not only include the preservation of graft function but also prevention and treatment of complications as well as scan for malignancy. Pathologists' role in evaluating histological changes of liver grafts aims at providing more information for clinicians and hepatologists to select the most appropriate treatment methods, to care for patients with liver transplantation effectively and in an optimal way.

Tạo bộ sưu tập với mã QR