This article introduces the structural and calculation requirements for steel beams with openings in the web, including: irregular hexagonal or oval openings, special cases are castellated (regular hexagonal) and cellular (round) openings. Calculation requirements, including verified the strength and deflection of the beam. Performing a numerical example for a beam with a opening in the web by zigzag cutting the web of the I-shaped steel beam, then butt-welding the cut part to form a regular hexagonal opening. The calculation steps show the implementation sequence, from material selection, load calculation, bending verified strength, verified buckling and deflection. Through numerical examples, to clarify the steps of designing steel web beams according to Vietnam's standard Design of steel structure TCVN 5575 (draft version 2023).