METABOLIC SYNDROME IN CANCER PATIENTS AFTER CHEMOTHERAPY IN THAI NGUYEN NATIONAL HOSPITAL

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Tác giả: Thị Hoa Nguyễn, Thị Kim Phượng Trần

Ngôn ngữ: Vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học và Công nghệ Đại học Thái Nguyên, 2020

Mô tả vật lý:

Bộ sưu tập: Metadata

ID: 421455

Thêm vào giỏ Liên kết toàn văn

Nghiên cứu nhằm xác định nồng độ một số chỉ số hóa sinh liên quan đến hội chứng chuyển hóa (HCCH) ở bệnh nhân ung thư sau hóa trị. Bằng phương pháp mô tả, theo dõi dọc 266 bệnh nhân được hóa trị ít nhất 6 chu kỳ (CK) tại Trung tâm Ung bướu, Bệnh viện Trung ương Thái Nguyên. Kết quả cho thấy sau hóa trị CK6, một số đặc điểm lâm sàng liên quan đến HCCH gồm cân nặng, chỉ số BMI, huyết áp đều cao hơn so với trước hóa trị (p>
0,05)
nồng độ glucose và một số thành phần lipid huyết tương như cholesterolTP, triglycerid, LDL-C đều cao hơn có ý nghĩa so với trước hóa trị, nồng độ HDL-C huyết tương thấp hơn có ý nghĩa so với trước hóa trị. Tỷ lệ tăng huyết áp là 31,9%, tỷ lệ tiền đái tháo đường là 21,4%, tỷ lệ đái tháo đường là 7,4%, tỷ lệ rối loạn ít nhất một thành phần lipid huyết tương là 64,3%, tỷ lệ HCCH là 22,9%. Có sự tăng một số chỉ số thuộc HCCH ở bệnh nhân sau hóa trị. Tỷ lệ HCCH là 22,9%., Tóm tắt tiếng anh, Study to determining the levels of plasma some biochemistry test related to metabolic syndrome in levels in cancer patients before and after chemotherapy. By a longitudinal study method of 266 cancer patients were treated at least 6 cycles of chemotherapy in Oncology department in Thai Nguyen National hospital. The results show that after the 6th cycle, some characteristics of metabolic syndrome include weight, BMI and blood pressure were higher than before chemotherapy (p>
0.05). Fasting levels of plasma glucose, total cholesterol, triglycerides, LDL-C were significantly higher than before chemotherapy, fasting levels of plasma HDL-C was significantly lower than before chemotherapy. The hypertension was 31.9%, the prediabete was 21.4%, the diabete was 7.4%, the at least one component of lipid profile disorder was 64.3%, the metabolic syndrome was 22.9%. After chemotherapy statistically significantly increases some component of metabolic syndrome. The metabolic syndrome was 22.9%.

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