Digital transformation in education can be understood as the process of comprehensive innovation of teaching methods, learning methods and in its education management work. Digital transformation in higher education is an objective need because of the following reasons: actively assiting teachers to reduce attendance check, marking, submitting teaching dossiers, and in using modern technology to activate classes... Additionally, digital transformation helps learners update documents effectively, diversify learning methods, update task requirements quickly and conveniently. The article aims to provide some solutions to promoting opportunities and overcoming challenges for fast, smooth and successful digital transformation in higher education in Dong Thap University.