Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation.

• Tác giả: Peter A Crawford, D André d'Avignon, Kyle Fulghum, Jacob R Gillingham, Xianlin Han, Abdirahman Hayir, Zahra Moazzami, Alisa B Nelson, Patrycja Puchalska, Eric D Queathem, Hai-Bin Ruan, Alisha Seay, David B Stagg
• Ngôn ngữ: eng
• Ký hiệu phân loại: 296.1121 Sources
• Thông tin xuất bản: United States : Science advances , 2025
• Bộ sưu tập: NCBI
• ID: 434305

Tóm tắt

Ketogenesis is a dynamic metabolic conduit supporting hepatic fat oxidation particularly when carbohydrates are in short supply. Ketone bodies may be recycled into anabolic substrates, but a physiological role for this process has not been identified. Here, we use mass spectrometry-based