In recent years, life skills education for children in preschools in Dis-trict 10, Ho Chi Minh City has always received significant attention. Life skills ed-ucation is regularly integrated into activities in a natural way so that children can acquire knowledge, have the ability to decide on their own activities, and know how to handle and prevent different situations from occurring in life. However, the training of life skills for children is still limited and there have been no positive changes. This article briefly introduces the results of research on managing life skills education activities for children in District 10, Ho Chi Minh City.