The objective of this study is to analyze the factors affecting the students' satisfaction with e-learning services. Technology adoption model and successful information system theory are applied to propose model and test hypotheses. The data were collected from 267 students who studied via e-learning platform at some universities in Ho Chi Minh City. The results show that perceived ease of use, perceived usefulness, information quality, system quality, instructor, support services, subjective norm, and perceived behavior control positively affects learners' satisfaction. In addition, implications were proposed for educational institutions to enhance students' satisfaction through enhancing the quality of elearning services.