Inducement of apoptosis in HepG2 cells by total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay

• Tác giả: Dang Khoa Dang, Trung Cang Diep, Nghia Son Hoang, Thanh Long Le, Le Huy Thinh Nguyen, Thi Phuong Thao Nguyen, Trung Quynh Nhu Nguyen, Xuan Dai Truong
• Ngôn ngữ: vie
• Thông tin xuất bản: Tạp chí Khoa học Trường Đại học Sư phạm Thành phố Hồ Chí Minh , 2019
• Bộ sưu tập: Metadata
• ID: 450596

Tóm tắt

This study aimed to evaluate the effect of total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay on HepG2 cell line. The results showed that total extract reduced HepG2 cell density for 48 hours of treatment. The total extract induced the changes expression of apoptosis-related genes in HepG2 cells including Bcl-2 and caspase family. Moreover, the ratio of apoptotic cells was associated with an increase of total extract concentration.