Objective: Single-incision laparoscopic surgery transabdominal preperitoneal (SILS-TAPP) inguinal hernia (IH) repair represents an innovative advancement in minimally invasive surgical techniques. However, there have been concerns about the complication rate of this technique. We aimed to systematically review the complications of SILS-TAPP in detail. Methods: We comprehensively searched the published literature between 1980 and 2022 on Pubmed, Embase, Scopus, Web of Science, and Proquest. Studies of IH patients aged <
18 who underwent SILS-TAPP were included. The results must include the intraoperative and/or postoperative complications rate of surgery. Studies not in English, studies of patients who underwent another surgery apart from hernia repair, and review articles were excluded. The abstract and full-text screening were done. Results: Primary search on a major database platform gained 348 records of articles. After screening, 9 studies were included. Nine studies recruited 1561 patients. Men were dominant. Recurrent IH accounted for about 4%. Two studies reported using specialized laparoscopic instruments (Roticulator), while the other eight used conventional instruments. No major intraoperative complications were reported. Blood loss was minimal. There was only one case wherein an additional trocar was placed. Postoperative complications were observed in about 5% of cases, including seroma, hematoma, urinary retention, port site infection, ileus, foreign body sensation, and port site hernia. Recurrence was rare, accounting for about 0.3%. Conclusion: Complications of SILS-TAPP are not frequent and mild. The recurrent rate is small. Therefore, SILS-TAPP can be a good alternative for open and laparoscopic hernia repair.