This article studies the benefits of using mobile technology to personalize students’ vocabulary learning. The article provides an overview of personalized learning, the meaning of personalized learning, the role of technology in personalizing learning, and applications that help personalize word learning. At the same time, the article also points out the challenges when applying mobile technology to teaching vocabulary and how to limit these challenges. The article concludes that the trend of applying mobile technology to teaching in general and personalizing vocabulary learning in particular is an inevitable trend.