In recent years, educational researchers globally and in Vietnam have shown great interest in studying the use of multimedia in teaching English, particularly for motivating learners and encouraging their participation and cooperation in learning foreign languages. However, the impact of these innovative methods on students’ communication skills in regions like the Northern Mountainous area of Vietnam, specifically Thai Nguyen Province, has not been thoroughly examined. This paper presents a study conducted on first-year students at Thai Nguyen University of Medicine and Pharmacy during the 2023-2024 academic year. The study employed an experimental design to assess the significance of using multimedia in English teaching. This design was utilized not only to evaluate the effectiveness of multimedia in English instruction but also to compare it with the traditional teaching methods currently in use.