The strong development of the 4.0 industrial revolution has created an information explosion, and the growing amount of human knowledge has been posing the problem of accessing and applying knowledge in teaching and learning activities. learning for university lecturers and students. Along with that, the requirements of credit-based training at universities have made students' self-study activities become a learning task. The subject Marxist-Leninist Political Economy is a theoretical science subject associated with practical connections to the country's socio-economic situation. Therefore, to achieve high efficiency in teaching Marxist-Leninist Political Economy, guiding students to self-study during the process of studying this subject plays an important and necessary role at Ha Long University.