Clinical microbiologists face many challenges in their academic, research, and teaching activities as a result of the rapid expansion of medical knowledge, which encompasses new pathogens, infections, antibiotic resistance mechanisms, laboratory techniques, and treatments. In clinical microbiology, this has made learning, studying, and teaching more difficult. E-learning makes schooling more flexible and useful. At this point, E-learning tools are very important for getting new skills and information quickly and on time. An overview of E-learning education in clinical microbiology and infectious illnesses is attempted in this article. The concepts, typical E-learning approaches, and widely used digital technologies are covered in it. Present are the clinical microbiology resources and applications.